What We Do
ClinOx, and the internationally acknowledged network of clinical centres with
whom we work, have the skills and experience to offer a wide range of services
which can be tailored to meet the individual needs of its industry clients,
whether pharmaceutical company or biotechnology firm. By working with its
industry clients and the early phase clinical trials centres, ClinOx can
provide the following services:
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improved quality of the clinical trial protocol – ClinOx provides access to a
"brains-trust" (cross-discipline therapy area expertise), thereby offering the
opportunity to develop and refine the client’s clinical protocol. By tapping
into this “brains-trust”, ClinOx can add value to its client’s product by
improving the design and execution of sophisticated early phase clinical
trials, including pharmacokinetic (PK), mechanistic pharmacodynamic (PD) and
pharmacogenetic (PGx), and imaging (PET, MRI) endpoints. Many of the ClinOx
investigators are already known to its industry clients because of their
individual reputations for excellence in clinical validation of research
hypotheses in early phase oncology trials;
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productive relationships with centres of scientific and clinical excellence
appropriate for current and future trials – ClinOx works with its industry
clients to identify, broker and maintain sustained and productive relationships
with clinical trial centres; and
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rapid, efficient and
cost-effective trial start up – ClinOx aims for rapid study site activation
through:
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rational approach to contractual negotiation and agreement – ClinOx
can negotiate and manage standard contracts for each trial with selected
centres. Contractual agreement is built upon the principle of consistent and
transparent costs for laboratory and clinical services. Master agreements
between ClinOx and industry clients enable efficient start-up of current and
future trials;
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managed approach to ethical and regulatory approval – in parallel with
contractual negotiation and agreement, ClinOx can work with its industry
clients to construct packages for timely ethical and regulatory approval; and
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trial management and improved data quality – ClinOx is continually
improving the quality and consistency of laboratory and clinical data by
ensuring that milestones and endpoints are clearly agreed between industry
clients and principal investigators; and by ensuring a highly trained workforce
utilise industry standard tools. ClinOx works with its industry clients to
conduct appropriate monitoring of the trials.